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Archive for Category: novità terapeutiche en

Jun 23 2023

Virus del nilo occidentale

Updates on Novel Non-Replacement Drugs for Hemophilia

novità terapeutiche en

Over the last decade, the world of hemophilia has experienced an unprecedented therapeutic advance,...

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May 30 2022

Managing invasive procedures in haemophilia patients with limited resources, extended half-life concentrates or non-replacement therapies in 2022

novità terapeutiche en

New treatment possibilities and modalities are now available globally for patients with haemophilia requiring...

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May 23 2022

Eptacog beta efficacy and safety in the treatment and control of bleeding in paediatric subjects (<12 years) with haemophilia A or B with inhibitors

novità terapeutiche en

Introduction: Eptacog beta is a new recombinant activated human factor VII bypass- ing agent...

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Apr 25 2022

PREDICTING INDIVIDUAL CHANGES IN TERMINAL HALF-LIFE AFTER SWITCHING TO EXTENDED HALF-LIFE CONCENTRATES IN PATIENTS WITH SEVERE HEMOPHILIA

novità terapeutiche en

Predicting individual effects of switching from standard half-life (SHL) to extended half-life (EHL) FVIII/FIX...

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Mar 28 2022

Confirmed long-term safety and efficacy of prophylactic treatment with BAY 94–9027in severe haemophilia A: final results of the PROTECT VIII extension study

novità terapeutiche en

Introduction: The phase 2/3 PROTECT VIII main study demonstrated efficacy and safety of BAY 94-9027...

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Feb 17 2022

Real-World Rates of Bleeding, Factor VIII Use, and Quality of Life in Individuals with Severe Haemophilia A Receiving Prophylaxis in a Prospective, Noninterventional Study

novità terapeutiche en

Regular prophylaxis with exogenous factor VIII (FVIII) is recommended for individuals with severe haemophilia...

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Feb 17 2022

Clinical outcome and adherence rate in Scandinavian patients with intermediate-intensity prophylaxis before and after the switch of standard half-life FVIII products to BAY 81–8973

novità terapeutiche en

Introduction: Treatment optimization in haemophilia A can be achieved by choice of FVIII product...

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Feb 17 2022

Invasive procedures in patients with haemophilia: Review of low-dose protocols and experience with extended half-life FVIII and FIX concentrates and non-replacement therapies

novità terapeutiche en

The performance of surgery and invasive procedures in patients with haemophilia is currently facing new...

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Nov 11 2021

Mortality in congenital hemophilia A – a systematic literature review

novità terapeutiche en

Against a background of a rapidly evolving treatment landscape, a contemporary, evidence-based consolidated understanding...

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Nov 09 2021

Establishment of a framework for assessing mortality in persons with congenital hemophilia A and its application to an adverse event reporting database

novità terapeutiche en

Abstract Background: Despite recent therapeutic advances, life expectancy in persons with congenital hemophilia A...

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