Statement on the second meeting of the International Health Regulations Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV)
The second meeting of the Emergency Committee convened by the WHO Director-General under the International Health Regulations (IHR) (2005) regarding the outbreak of novel coronavirus 2019 took place on Thursday, 30 January 2020. China quickly identified the virus and shared its sequence, so that other countries are now able to diagnose it quickly and protect […]
Transmission of 2019-nCoV Infection from asymptomatic contacts in Europe and USA
Testo abstract:Coronavirus (2019-nCoV) from Wuhan is raising concerns in the health care community as the virus is spreading around the world. After being identified in late December 2019, the number of cases of Coronavirus (2019-nCoV) infections imported from China into other countries is increasing and its epidemiology is changing daily basis. In detail, in the […]
New physiotherapy concepts in hemophilia
Until the ’70s, hemophiliacs did not have great means and opportunities to improve the quality of life, they lived in a voluntary “segregation” due to a progressive disability, lacking therapeutic and rehabilitative supports properly for recovering physical activity . Subsequently, replacement therapy was developed with concentrates of the coagulation factors of which they were deficient […]
Physical exercise and rehabilitation in hemophilia
Physical exercise Physical exercise in patients with hemophilia (PWH) currently is used to heal faster after bleeding and to restore muscle-joint function in subjects with chronic arthropathy. Aquatic, stretching, proprioceptive and aerobic exercises are the most usual in PWH A and B of any severity. A Cochraine Database Systematic Review published in 2016 analyzed randomized […]
Bleeding and liver transplantation outcomes in haemophilia
Abstract BACKGROUND: Hepatitis C is the major cause of end-stage liver disease and the major indication for orthotopic liver transplantation (OLTx) in individuals with haemophilia. AIM: To assess the epidemiology and outcomes of OLTx in U.S. haemophilia patients. METHODS: We investigated haemophilia liver transplant recipients between 1993 and 2012, using the Nationwide Inpatient Sample, identified […]
Early start of the West Nile fever transmission season 2018 in Europe
In Europe, surveillance indicates that the 2018 West Nile fever transmission season started earlier than in previous years and with a steeper increase of locally-acquired human infections. Between 2014 and 2017, European Union/European Economic Area (EU/EEA) and EU enlargement countries notified five to 25 cases in weeks 25 to 31 compared with 168 cases in […]
An early start of West Nile virus seasonal transmission: the added value of One Health surveillance in detecting early circulation and triggering timely response in Italy, June to July 2018.
Abstract In Italy, the 2018 West Nile virus transmission season started early with a high number of cases reported. One-Health surveillance, within the Italian West Nile national preparedness and response plan, detected viral circulation 9 days before symptom-onset of the first confirmed human case; triggering timely implementation of blood and transplant safety measures. This is […]
14 February 2020
Statement on the second meeting of the International Health Regulations Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV)
The second meeting of the Emergency Committee convened by the WHO Director-General under the International Health Regulations (IHR) (2005) regarding the outbreak of novel coronavirus 2019 took place on Thursday, 30 January 2020. China quickly identified the virus and shared its sequence, so that other countries are now able to diagnose it quickly and protect […]
24 March 2020
Coronavirus Disease 2019: Coronaviruses and Blood Safety
With the outbreak of unknown pneumonia in Wuhan, China, in December 2019, a new coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), aroused the attention of the entire world. The current outbreak of infections with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19). The World Health Organization declared COVID-19 in China as a Public Health Emergency of International Concern. Two other coronavirus infections-SARS in 2002-2003 and […]
17 January 2018
Epidemiological characteristics of human prion diseases
In the absence of specific therapies for human prion diseases, which are frequently associated with neurodegenerative disorders with fatal outcome, only an active surveillance can be used to monitor and prevent the transmission of such diseases. For this reason, starting from 1993, surveillance systems have been established in many countries. Moreover, there is urgent need […]
12 March 2020
INACTIVATION OF THREE EMERGING VIRUSES – SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS, CRIMEAN-CONGO HAEMORRHAGIC FEVER VIRUS AND NIPAH VIRUS – IN PLATELET CONCENTRATES BY ULTRAVIOLET C LIGHT AND IN PLASMA BY METHYLENE BLUE PLUS VISIBLE LIGHT
Emerging viruses like severe acute respiratory syndrome coronavirus (SARS-CoV), Crimean-Congo haemorrhagic fever virus (CCHFV) and Nipah virus (NiV) have been identified to pose a potential threat to transfusion safety. In this study, the ability of the THERAFLEX UV-Platelets and THERAFLEX MB-Plasma pathogen inactivation systems to inactivate these viruses in platelet concentrates and plasma, respectively, was […]
27 January 2020
DAMOCTOCOG ALFA PEGOL: A REVIEW IN HAEMOPHILIA A
Damoctocog alfa pegol (Jivi®) is approved in the USA, EU, Japan and Canada for the treatment and prophylaxis of previously treated patients aged ≥ 12 years with haemophilia A. Formulated with a 60 kDa polyethylene glycol (PEG) moiety, damoctocog alfa pegol is an intravenously (IV) administered recombinant factor VIII (rFVIII) product with a longer terminal half-life than non-PEGylated FVIII […]